Withington is a suburban area of the City of Manchester, in Greater Manchester, England. It lies 4 miles (6.4 km) south of Manchester city centre, about 0.4 miles (0.6 km) south of Fallowfield, 0.5 miles (0.8 km) north-east of Didsbury, and 1 mile (1.6 km) east of Chorlton-cum-Hardy, near the centre-to-south edges of the Greater Manchester Urban Area; in the Manchester Withington parliamentary constituency. Withington is a dormitory village consisting of a resident population slightly over 14,000 people.

Today, the residents of Withington comprise a mixture of families, university students and "young professionals"—often themselves former students.[4] This is in a large part due to its education links—particularly the proximity to the University of Manchester, which has the largest student population in the United Kingdom, and Manchester Metropolitan University. As a consequence, Withington is predominantly an area of mixed affluence. It is also a centre for clinical excellence with one of the largest cancer treatment centres in Europe—Christie Hospital—and Withington Community Hospital.